A new and unique treatment has been developed for the treatment of osteoarthritis that focuses on the root causes of the problem rather than the consequences. When the articular cartilage is damaged, collagen fibers are revealed from the joint surface, which the body's immune system interprets as harmful and tends to destroy. Through so-called oral tolerance, cells in the intestinal defense system can be “accustomed” to the presence of damaged tissue with regular oral collagen antigen (UC-II) - and thus break the self-feeding vicious circle. Equistro Flexadin® II UC-UC containing undenatured collagen II, which recognizes the gut defense system. UC-II studies have shown very good results in the supportive care of osteoarthritis.